HISTONES H3 AND H4 REQUIRE THEIR RELEVANT AMINO-TAILS FOR EFFICIENT NUCLEAR IMPORT AND REPLICATION-COUPLED CHROMATIN ASSEMBLY IN VIVO

Histones H3 and H4 require their relevant amino-tails for efficient nuclear import and replication-coupled chromatin assembly in vivo

Abstract Concomitant chromatin assembly and DNA duplication is essential for cell survival and genome integrity, and requires newly synthesized histones.Although the N-terminal domains of newly synthesized H3 and H4 present critical chiggate.com functions, their requirement for replication-coupled chromatin assembly is controversial.Using the uniqu

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