Histones H3 and H4 require their relevant amino-tails for efficient nuclear import and replication-coupled chromatin assembly in vivo
Abstract Concomitant chromatin assembly and DNA duplication is essential for cell survival and genome integrity, and requires newly synthesized histones.Although the N-terminal domains of newly synthesized H3 and H4 present critical chiggate.com functions, their requirement for replication-coupled chromatin assembly is controversial.Using the uniqu